Temperature requirements through the suppository production

Suppositories are usually designed to dissolve at body temperature, similarly such products need to be dried, which is done at low temperatures with very dry air, where dehumidifiers are also used. Suppositories need to be manufactured in a cool dry environment to prevent absorption of moisture etc.

While suppositories generally do not have high temperature and humidity requirements, usually 18-26°C, 45-65%

However, suppositories made with polyethylene glycols, polyoxyl stearate, and poloxamer are more sensitive to humidity, more hygroscopic and prone to deformation when exposed to moisture.